Learn how the popular CBD compound affects your thyroid health in this article.. Learn more about hypothyroidism with Paloma Health Can You Take CBD Oil With Levothyroxine? Drug interaction is defined as the changes in a drug’s effects due to recent or concurrent use of another drug or drugs (drug-drug interactions), Read about CBD Oil and Thyroid Medication ✅ – Health Magazine Health, Medicine, Fitness, Nutrition, Endocrine News
How Does CBD Affect Your Thyroid Hormones?
CBD has taken the health community by storm. Indeed, this chemical compound appears in nearly all types of products, addressing all kinds of health concerns. From supplements and oils to shampoos and cosmetics, CBD is seemingly in all sorts of health goods. Because CBD has been widely available for so little time, we are still trying to learn precisely how it affects different body systems. For people with a thyroid condition, this is what we know so far about how CBD affects your thyroid gland and related thyroid hormone levels.
What is CBD?
CBD stands for cannabidiol. It is one of the most active ingredients of cannabis (or marijuana). It is in higher quantities in its sister plant, hemp. CBD does not create a “high” or have a psychoactive component like THC when used alone.
CBD is an oil extracted from hemp seeds. This oil is often full of healthy fats, often appearing in beauty products such as moisturizers and facial serums.
One of the most well-known and proven medical uses for CBD is managing certain types of epilepsy, especially in children. Indeed, even an FDA-approved medication (Epidiolex) contains CBD to treat a particular type of seizure condition. Beyond treating certain types of epilepsy, there is no concrete scientific evidence supporting using CBD to treat other health conditions.
With that said, numerous people and their health providers believe that CBD helps with a robust amount of health complaints and conditions, such as chronic pain, cancer pain, and joint pain.
Despite the absence of enough scientific evidence, people also use CBD oil is to anecdotally help with:
- Sleep issues
- Anxiety disorders (PTSD, panic disorders, etc.)
- Topical pain relief
- Reducing inflammation
- Hot flashes
- Neurodegenerative diseases
The endocrine and endocannabinoid systems
The endocrine system
The endocrine system is the collection of glands that release hormones. Hormones are chemical messengers that help one part of the body communicate with another part of the body.
Endocrine glands are throughout the body, and hormones constantly give and receive feedback to keep the body functioning optimally. The hypothalamus, pituitary gland, and pineal gland are all located in the brain. The thyroid and parathyroid glands are in the neck. The thymus is between your lungs. The adrenal glands are on top of your kidneys. The pancreas is behind your stomach. Ovaries or testes are located in the pelvic region.
Levels of hormones naturally fluctuate depending on the time of day and stage of life (for instance, pregnancy or menopause). However, hormones can also become imbalanced in a way that requires treatment from your healthcare provider. Such is the case with hypothyroidism, the condition in which an underactive thyroid gland does not produce enough thyroid hormones.
As part of the endocrine system, the thyroid gland helps regulate the body’s metabolism in the form of blood pressure, blood temperature, and heart rate. When your thyroid hormone production drops, your body processes slow down and change.
The endocannabinoid system
Science is starting to understand how the body responds to cannabinoids. Endocannabinoids are molecules that the body produces naturally in small amounts that act on cannabinoid receptors. The endocannabinoid system is a highly complex cellular signaling system that plays an important modulatory role in the brain, endocrine, and immune functions.
The endocannabinoid system in the body plays a role in:
In particular, the endocannabinoid systems seem to play a critical role in regulating reproductive hormones and our stress response. This system also helps to control food intake and related energy expenditure.
Within this system, the mechanics include endocannabinoids, cannabinoid receptors, and enzymes. The body naturally produces endocannabinoids, which are molecules that are similar to cannabinoids. The cannabinoid receptors within this system respond to endocannabinoids, but they also bind to THC, which is one reason why THC can have so many effects on your body,
Because CBD is different from THC, it has a different interaction with the endocannabinoid system. CBD does not appear to bind to receptors like THC but instead may prevent endocannabinoids from breaking down or attaching to a receptor for which researchers have not yet been able to identify.
Does CBD impact thyroid hormones?
Because the endocannabinoid system has the potential to affect every system in the body, there is potential that CBD may influence your endocrine system, too.
We know that endogenous cannabinoids (the ones produced by our bodies) help regulate our appetite, energy, homeostasis, and influence endocrine glands, including the pituitary gland and thyroid gland. Research does not yet know how external cannabinoids (like CBD) affect these glands and your serum thyroid hormones concentrations like TSH and T4.
What does using CBD mean for people taking thyroid medication?
Cannabinoids and thyroid hormones both play a role in regulating your metabolism. While we do not know exactly how CBD affects your metabolism, there is potential that synthetic thyroid hormone replacement medication and CBD may compete to regulate your metabolism.
Aside from uncertainties in how CBD and thyroid medication interact, there is some evidence that CBD helps reduce inflammation, which is at the root of Hashimoto’s disease, one of the leading causes of hypothyroidism. Indeed, it has immunosuppressant-like qualities, making it a potentially valuable substance for certain autoimmune diseases like Hashimoto’s.
Suppose you have a thyroid condition and are managing it with medication. In that case, you need to practice caution when introducing other substances which may alter your system.
Your Guide To Thyroid Medication
Optimizing your thyroid levels with thyroid hormone replacement medication is usually the first step in minimizing symptoms.
What should I do if I want to try a CBD product?
Finding balance in your thyroid levels can take a significant amount of trial and error and time. People often need to try different doses of thyroid hormone medication to see what brings their thyroid hormones to a therapeutic level. Many people also find that factors outside their medication can also throw off their thyroid function, including taking new medications and making diet changes.
If you want to try CBD, you should first check with your doctor to see if it is safe for you. It is important to know that CBD is not a regulated substance if you do get the go-ahead. The FDA considers it a dietary supplement, which are not generally monitored for quality, safety, and efficacy. This means that there is likely a lack of standardization in some CBD formulations. Thus, concentrations and strengths may differ, even in the same brand.
It is also important to keep in mind that some CBD manufacturers may make false claims of how CBD is a cure-all, even for diseases like cancer. Because there is little regulation on CBD and no concrete evidence for treating health conditions other than some types of epilepsy, it is best to explore using CBD in partnership with your doctor.
If you choose to try CBD and have checked with your doctor to rule out medication interactions, try to separate when you take your thyroid medication from when you use CBD to minimize the impact on the absorption of thyroid medication.
Can You Take CBD Oil With Levothyroxine?
Drug interaction is defined as the changes in a drug’s effects due to recent or concurrent use of another drug or drugs (drug-drug interactions), ingestion of food (drug-nutrient interactions), or ingestion of dietary supplements (dietary supplement-drug interactions).
Drug-drug interactions result when two or more drugs react with each other. Such drugs can be from a combination of prescription drugs and/or over-the-counter (OTC) medications. Drugs with a narrow therapeutic range (little difference between therapeutic and lethal dose) are more likely to face incidents of serious drug interactions.
What is levothyroxine?
Levothyroxine is a prescription medicine used to treat an underactive thyroid gland (hypothyroidism). The thyroid gland makes thyroid hormones that help to control energy levels and growth. Levothyroxine is taken to replace the missing thyroid hormone thyroxine.
Levothyroxine belongs to a class of drugs called hormones. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. About 40-60% of orally administered levothyroxine is absorbed; the majority from the jejunum and upper ileum of the gastrointestinal tract. Absorption is increased when levothyroxine is taken on an empty stomach. Levothyroxine works by providing the thyroid hormone that your thyroid gland would produce if it were working normally.
About 1 to 2 weeks after you start treatment with levothyroxine, you will likely notice that your levels of fatigue have improved. It is important that you take your medication exactly as prescribed and not miss any doses as well as maintain routine checkups with your primary health care provider.
What is CBD oil?
Cannabidiol (CBD) oil is a product that’s derived from cannabis. It’s a type of cannabinoid, which are the chemicals naturally found in marijuana plants. Even though it comes from marijuana plants, CBD doesn’t create a “high” effect or any form of intoxication — that’s caused by another cannabinoid, known as THC. This quality makes CBD an appealing option for those who are looking for relief from pain and other symptoms without the mind-altering effects of cannabis or other side effects related to some pharmaceutical drugs.
CBD oil is made by extracting CBD from the cannabis plant and then diluting it with a carrier oil like coconut oil or hemp seed oil. CBD can be found in a variety of products online and in stores, including dietary supplements, bath soaks, drinks, and food.
It continues to gain momentum in the health and wellness world, with some scientific studies finding that it may ease symptoms of several conditions. A high-quality CBD oil may address a variety of thyroid dysfunctions. This underperformance includes hypothyroidism, hyperthyroidism, goiter, thyroiditis, and thyroid storm. All of the above conditions are triggered by chronic inflammation of the thyroid gland due to the body’s autoaggressive actions on this organ.
We know that endogenous cannabinoids (the ones produced by our bodies) help regulate our appetite, energy, homeostasis, and influence endocrine glands, including the pituitary gland and thyroid gland. Research does not yet know how external cannabinoids (like CBD oil) affect these glands and your serum thyroid hormones concentrations like TSH and T4.
A 2015 study found significant concentrations of CB1 and CB2 cannabinoid receptors in the thyroid glands. These receptors were associated with the shrinkage of thyroid tumors, showing promise as potential blockers of the spread of malignant cells on the gland.
Can you take CBD oil with levothyroxine?
No, you should never take CBD oil with levothyroxine together, because taking CBD oil with other medications that have similar effects like levothyroxine may increase the risk of unwanted symptoms or toxicity.
In addition, taking CBD oil while on levothyroxine treatment can lead to hyperthyroidism, a condition where your thyroid makes and releases high levels of thyroid hormone. This condition can speed up your metabolism. Symptoms of hyperthyroidism include a rapid heartbeat, weight loss, increased appetite, and anxiety.
Researchers are working to determine the specific interactions between CBD and various medications. Studies have been done on animals for certain medications, but in many cases, scientists are still determining how those results translate to humans.
CBD Oil and Thyroid Medication
Thyroiditis and the condition in which it develops into, hypothyroidism, is a debilitating disease which many people suffer from daily. The question has been raised concerning just how CBD oil interacts with thyroid medications? Here in this article we will detail the specificities behind CBD oil and Thyroid medication; equipping you with the knowledge that you need to use your CBD oil with a peace of mind.
What is Thyroiditis?
Hashimoto’s thyroiditis, also called autoimmune or chronic lymphocytic thyroiditis, is the most common form of thyroiditis. As the disease begins to advance the cells of the thyroid gland becomes inefficient at converting iodine into thyroid hormone. As a result, the thyroid gland compensates by enlarging itself.
As the disease continues to progress the thyroid stimulating hormone increases. A different thyroid hormone called the T4 decreases making the individual experience hypothyroidism. It is important to note that the progression of this disease can vary from a few weeks to several years.
Is there a negative reaction between CBD Oil and Thyroid Medication?
Interaction between cannabinoids and some thyroid medications is a result of the fact that these substances compete for metabolism. More specifically, these two substances compete in the cytochrome P450 pathways to be metabolized. Consequently, this interaction would most likely cause hyPERthyroidism because more thyroxine would accumulate before the body metabolizes it. In addition to this, some have reported that they experienced mild nausea and anxiety if they took the thyroid medication and the CBD oil too closely together. However, if a few hours were allotted between the medications, there seemed to be no negative side effects for most people. Of course, this depends on the dosage abs frequency of use for both thyroid meds and the CBD oil.
*With that being said, it is important to keep in mind that there haven’t been many studies that have reported adverse results from the use of CBD oil while having thyroid issues.
Furthermore, because hypothyroidism is a disease fueled by inflammation, CBD oil is an excellent candidate to offer relief. CBD oil is a natural immunosuppressor—in other words, it suppresses of lessens the effectiveness of the immune system and responses. Therefore, if possible, you should try to incorporate this into your regimen if you are not affected by taking the two medications together.
It is important to be aware if any ingredients can cause undesirable side effects if consumed. Thankfully, CBD oil is an all-natural ingredient that doesn’t contain other chemicals that shouldn’t interfere with the efficacy of other meds. Nonetheless, always thoroughly research the ingredients in any medications you choose to ingest.