Posted on

cannabis seeds thc content

Cannabis seeds thc content

Δ 9 -THC is a nonselective partial agonist of the CB1 and CB2 receptors, and elicits a variety of physiological effects, including analgesia, appetite stimulation, motor neuron inhibition, and CNS sedation, when bound to CB1. 12 Δ 9 -THC is highly potent and has a Ki <50 nM for both CB1 and CB2 in humans. 13 In a study involving adult males who were infrequent users of cannabis, a 15 mg oral dose of THC was found to impair episodic memory and increase task error rates, 2 h after its administration. 14 Based on the results obtained in this study, 120 g of hemp seeds from brand# 1 could contain an equivalent quantity of 15±3 mg of total Δ 9 -THC, using the quantity estimates from SFE. Suggested serving size for an adult for most consumer brands of hemp seeds is 30 g, and this is equivalent to 3.8±0.6 mg of total Δ 9 -THC, when using brand# 1 hemp seeds. It is also noted that a significant portion of the total Δ 9 -THC content exists in the form of the acid precursor Δ 9 -THCA, which is not known to exhibit psychoactivity. 15 However, exposure to heat (due to cooking or other reasons) could always generate Δ 9 -THC. However, in the absence of strong heating, the seeds’ effective Δ 9 -THC concentration is expected to be lower than their total Δ 9 -THC content, lowering the risk of acute phytocannabinoid poisoning from direct consumption. Chinello et al. reported a case of subacute poisoning from the sustained consumption of a relatively Δ 9 -THC-poor product by a toddler. 9 Such subacute poisoning is always a possibility when hemp seeds carry higher quantities, such as 10- and 12-fold higher than the recommended limits, or the concentrations of Δ 9 -THC are not estimated accurately.

4. Supercritical fluid extraction (SFE). Hemp seeds (1 or 2 g) were macerated with a mortar and pestle, reweighed, and transferred to an extraction vessel. The extraction was performed using supercritical CO2 as solvent A and ethanol as solvent B. The photodiode array detector was used to monitor the extract, with the range set to 200–600 nm. The back-pressure regulator was set to 12 MPa for the SFE, and other conditions include the following: flow rate=10 mL/min for both CO2 and slave pumps, and 1 mL/min for the make-up pump; temperature=40°C; and gradient: 0–25 min: solvent A, 100%→50%, and solvent B, 0%→50%; 25–26 min: solvent B, 100%; and 26–30 min: solvent A, 100%. The acquisition time was 30 min and the total run time was 30.2 min. All fractions were combined and concentrated to dryness under reduced pressure at 25°C to obtain the extract as a resin (yield: 31–37%).

2 Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

Conclusion: Careful consideration of the extraction method is very important for the measurement of cannabinoids in hemp seeds.

Results and Discussion

1 Center for Molecular Design and Preformulations, Toronto General Hospital Research Institute, University Health Network, Toronto, Canada.

2 Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.

For brand# 3, three extraction methods concurred with the estimation of the phytocannabinoids, viz. microwave extraction, sonication, and SFE estimated the CBD in the rage of 7±9 μg/g to 21±9 μg/g, and total Δ 9 -THC content in the range of 11±4 to 23±4 μg/g hemp seeds ( Fig. 2C ). However, Soxhlet extraction indicated that the amount of CBD and total Δ 9 -THC in brand# 3 hemp seeds to be 90±51 and 91±28 μg/g of hemp seeds, respectively. While the former estimations indicate that total Δ 9 -THC is closer to the legal limit in hemp seeds, the latter method indicated it to be up to nine folds higher than the legal limit, and this is a significant difference. Overall, none of the brands using any of the methods could convincingly be confirmed that the total Δ 9 -THC content is within the legal limits of 10 μg/g of hemp seeds. It is also noted that the phytocannabinoid content exhibited a significant variation even among batches from the same brand, reflecting both the inhomogeneous nature of seeds as well as the variations in quantification based on the extraction process.

Materials and Methods

Total Δ 9 -THC (green bars) and CBD (blue bars) content (μg/g of hemp seed) in the consumer-grade hemp seeds, in brand# 1 (A), brand# 2 (B), and brand# 3 (C). Legal limit of Δ 9 -THC per gram of hemp seeds (as per Health Canada) is shown as a horizontal red line. CBD, cannabidiol; THC, tetrahydrocannabinol.

Total THC and total CBD are the total observed weights of THC and THCA, and CBD and CBDA.

Cannabis seeds thc content

Sure, 25% THC is potent, but why not find seeds that contain 35% THC? Once again, it’s all about you. Therefore, only you can decide if a 20-30% THC strain is right for your needs.

Effects

Wedding Cake’s flowers drip with resin as if they were dipped in confectioners sugar. Although Wedding Cake is a delicious strain, we’ll be surprised if you can remember your name after a second hit.

#8 Gelato

When you want the strongest weed possible, look no further than Bruce Banner #3.

Cannabis seeds thc content

What does Cannabis Sativa Seed Oil do for the skin?

What are the benefits of Cannabis Sativa Seed Oil?

What is the difference between cannabis, hemp and marijuana?

Stress is often an inevitable part of everyday life and can affect the skin in many different ways, from accelerated the visible signs of ageing, to dehydration, to irritation, to dullness and uneven skin tone and texture. Cannabis Sativa Seed Oil tackles the signs of stressed skin, calming, soothing and reducing the appearance of redness . Like every other organ in the body, the skin has its essential needs for optimal health and beauty. The most important two ingredients that a skincare product can contain are essential fatty acids and vitamin E. In nature Cannabis Sativa Seed Oil contains a balanced concentration of omega 3 and omega 6.

Cannabis Sativa Seed Oil is an herbaceous oil cold pressed from hemp seeds and has long been recognised for its use as a food and beauty ingredient. The use of Cannabis Sativa Seed Oil in skincare products has grown in popularity over the last few years as a result of an increasing consumer interest in using the power of plants in skincare formulations. This naturally green oil is composed of up to 90% omega fatty acids. Unlike CBD oil, Cannabis Sativa Seed Oil is mainly found in skincare products thanks to its powerful hydrating properties and abundant antioxidants.